Methionine329 in human serum albumin: A novel target for alkylation by sulfur mustard.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2548
Abstract: Exposure to the vesicant sulfur mustard (SM) may lead to erythema and blistering. Toxicity of SM is hypothesized due to the alkylation of DNA bases and nucleophilic amino acid side chains in proteins (adducts) by… read more here.
Keywords: sulfur mustard; serum; human serum; novel target ... See more keywords
Alkylated glutamic acid and histidine derived from protein-adducts indicate exposure to sulfur mustard in avian serum.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3236
Abstract: Sulfur mustard (SM, bis(2-chloroethyl)-sulfide) is a banned chemical warfare agent deployed in the violent conflict in the Middle East poisoning humans and animals. For legal reasons bioanalytical methods are mandatory proving exposure to SM. Reaction… read more here.
Keywords: avian serum; sulfur mustard; serum; hete ... See more keywords
Dermatotoxicology of sulfur mustard: Historical perspectives from World War I
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3524
Abstract: Sulfur mustard has been used as a chemical warfare agent for the past century. After its introduction by the Germans in World War I, investigators quickly began studying its impact on the human body including… read more here.
Keywords: sulfur mustard; dermatotoxicology sulfur; world war;
Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Toxicology"
DOI: 10.1007/s00204-021-03005-3
Abstract: Sulfur mustard (SM) is a chemical warfare agent which use is banned under international law and that has been used recently in Northern Iraq and Syria by the so-called Islamic State. SM induces the alkylation… read more here.
Keywords: dna; sulfur mustard; biomarker; exposure ... See more keywords
A novel exposure system generating nebulized aerosol of sulfur mustard in comparison to the standard submerse exposure.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.11.025
Abstract: Inhalation of the chemical warfare agent sulfur mustard (SM) is associated with severe acute and long-term pulmonary dysfunctions and health effects. The still not completely elucidated molecular toxicology and a missing targeted therapy emphasize the… read more here.
Keywords: exposure system; sulfur mustard; exposure; ali ... See more keywords
Skin decontamination efficacy of sulfur mustard and VX in the pig model: A comparison between Fuller's earth and RSDL.
Sign Up to like & getrecommendations! Published in 2021 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2021.109393
Abstract: Skin decontamination following exposure to chemical agents is a most important component of the individual defense doctrine, removing the agent, ceasing its penetration and preventing secondary contamination of the first responders. The goal of the… read more here.
Keywords: sulfur mustard; efficacy; decontamination; fuller earth ... See more keywords
High barrier properties against sulfur mustard of graphene oxide/butyl rubber composites
Sign Up to like & getrecommendations! Published in 2019 at "Composites Science and Technology"
DOI: 10.1016/j.compscitech.2018.12.002
Abstract: Abstract Protection against sulfur mustard (HD) is essential for the safety of the operators in the lab and in war. In this research, graphene oxide/butyl rubber (GO/IIR) composites were first prepared by a green method… read more here.
Keywords: sulfur mustard; barrier properties; graphene oxide; iir ... See more keywords
Alteration in serum levels of immunoglobulins in seriously eye-injured long-term following sulfur-mustard exposure.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.105895
Abstract: INTRODUCTION Sulfur mustard (SM) is a potent toxic agent that cause local and systemic changes in the human body such as dysregulation of the immunological system. This gas affects different organs such as lungs, skin,… read more here.
Keywords: sulfur mustard; two groups; exposure; level ... See more keywords
Delayed effects of sulfur mustard on autophagy suppression in chemically-injured lung tissue.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2019.105896
Abstract: BACKGROUND Autophagy is an intracellular hemostasis mechanism, responding to extracellular or intracellular stresses. Sulfur mustard (SM) induces cellular stress. Iranian soldiers exposed to SM gas, during the Iraq-Iran war, suffer from delayed complications even 30 years… read more here.
Keywords: sulfur mustard; effects sulfur; lc3 protein; delayed effects ... See more keywords
Sulfur mustard and biological ageing: A multisystem biological health score approach as an extension of the allostatic load in Sardasht chemical veterans.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108375
Abstract: BACKGROUND Mustard gas as a chemical weapon has been used in wars and its long-term side effects are substantial in the human body. This study was aimed to apply an extension of allostatic load, known… read more here.
Keywords: allostatic load; health score; biological health; sulfur mustard ... See more keywords
Bicarbonate-activated hydrogen peroxide and efficient decontamination of toxic sulfur mustard and nerve gas simulants.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2017.09.055
Abstract: 13C NMR spectra showed that peroxymonocarbonate (HCO4-) was generated in the NaHCO3-activated H2O2 solution and pH was a key factor in its production. A cycle for the bicarbonate anion was proposed as HCO3-→HCO3 → (CO2)2*→CO2(aq)→HCO4-… read more here.
Keywords: hco4; sulfur mustard; activated h2o2; gas ... See more keywords