Brain targeted delivery of sumatriptan succinate loaded chitosan nanoparticles: Preparation, In vitro characterization, and (Neuro-)pharmacokinetic evaluations
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102179
Abstract: Abstract Migraine is a neurovascular disorder characterized by nausea, vomiting, pain, photophobia, phonophobia, and in some cases auras. Because of the complexity of the pathophysiology of migraine and the limited systemic availability of sumatriptan succinate… read more here.
Keywords: loaded chitosan; chitosan nanoparticles; delivery; drug ... See more keywords
Intranasal drug delivery of sumatriptan succinate-loaded polymeric solid lipid nanoparticles for brain targeting
Sign Up to like & getrecommendations! Published in 2022 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2022.2090575
Abstract: Abstract Migraine is a frequent neurological condition characterized by throbbing headaches, nausea, photophobia, and phonophobia, among other symptoms. Sumatriptan belongs to a BCS class III, which exhibits poor oral bioavailability and several side-effects. The objective… read more here.
Keywords: brain targeting; microscopy; brain; sumatriptan succinate ... See more keywords
Fabrication of polyvinyl alcohol based fast dissolving oral strips of sumatriptan succinate and metoclopramide HCL
Sign Up to like & getrecommendations! Published in 2020 at "Science Progress"
DOI: 10.1177/0036850420964302
Abstract: Migraine is a throbbing condition, usually associated with nausea and vomiting and requires concurrent administration of anti-migraine along with anti-emetic therapy. The current study was undertaken with an aim to fabricate fast dissolving oral strips… read more here.
Keywords: fast dissolving; metoclopramide hcl; oral strips; dissolving oral ... See more keywords