Dissecting the genetics of complex traits using summary association statistics
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Genetics"
DOI: 10.1038/nrg.2016.142
Abstract: During the past decade, genome-wide association studies (GWAS) have been used to successfully identify tens of thousands of genetic variants associated with complex traits and diseases. These studies have produced extensive repositories of genetic variation… read more here.
Keywords: association statistics; genetics; summary association; association ... See more keywords
Improved Estimation of Phenotypic Correlations Using Summary Association Statistics
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.665252
Abstract: Estimating the phenotypic correlations between complex traits and diseases based on their genome-wide association summary statistics has been a useful technique in genetic epidemiology and statistical genetics inference. Two state-of-the-art strategies, Z-score correlation across null-effect… read more here.
Keywords: estimation; association statistics; summary association; association ... See more keywords