SUMOylation Inhibition Mediated by Disruption of SUMO E1-E2 Interactions Confers Plant Susceptibility to Necrotrophic Fungal Pathogens.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular plant"
DOI: 10.1016/j.molp.2017.01.007
Abstract: Protein modification by SUMO modulates essential biological processes in eukaryotes. SUMOylation is facilitated by sequential action of the E1-activating, E2-conjugating, and E3-ligase enzymes. In plants, SUMO regulates plant development and stress responses, which are key… read more here.
Keywords: sumoylation; sumo conjugation; plant; inhibition ... See more keywords
Sumoylation in plants: mechanistic insights and its role in drought stress.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of experimental botany"
DOI: 10.1093/jxb/ery233
Abstract: Post-translational modification by SUMO is an essential process that has a major role in the regulation of plant development and stress responses. Such diverse biological functions are accompanied by functional diversification among the SUMO conjugation… read more here.
Keywords: sumoylation; sumo conjugation; role drought; stress ... See more keywords
SUMO conjugation regulates the activity of the Integrator complex
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1055
Abstract: RNA pol II transcribes snRNA genes in close proximity to Cajal bodies, subnuclear compartments that depend on the SUMO isopeptidase USPL1 for their assembly. We show here that overexpression of USPL1 alters snRNA 3’-end cleavage,… read more here.
Keywords: integrator; integrator complex; sumo conjugation; activity ... See more keywords
The SUMO Conjugation Complex Self-Assembles into Nuclear Bodies Independent of SIZ1 and COP11[OPEN]
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DOI: 10.1104/pp.18.00910
Abstract: SUMO conjugation activity causes the formation of SUMO nuclear bodies, which strongly overlap with COP1-containing nuclear bodies due to a VP motif in the E3 ligase SIZ1 that acts as bridge protein. Attachment of the… read more here.
Keywords: sumo conjugation; cop1; conjugation activity; nuclear bodies ... See more keywords
SUMO-specific proteases and isopeptidases of the SENP family at a glance
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DOI: 10.1242/jcs.211904
Abstract: ABSTRACT The ubiquitin-related SUMO system controls many cellular signaling networks. In mammalian cells, three SUMO forms (SUMO1, SUMO2 and SUMO3) act as covalent modifiers of up to thousands of cellular proteins. SUMO conjugation affects cell… read more here.
Keywords: sumo conjugation; senp family; glance; isopeptidases senp ... See more keywords
Protein–Protein Interactions Facilitate E4orf6-Dependent Regulation of E1B-55K SUMOylation in HAdV-C5 Infection
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14030463
Abstract: The human adenovirus type C5 (HAdV-C5) E1B-55K protein is a multifunctional regulator of HAdV-C5 replication, participating in many processes required for maximal virus production. Its multifunctional properties are primarily regulated by post-translational modifications (PTMs). The… read more here.
Keywords: e1b 55k; hadv; 55k sumoylation; sumo conjugation ... See more keywords