Autophagy mediates SUMO-induced degradation of a polyglutamine protein ataxin-3
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DOI: 10.1080/19768354.2017.1330765
Abstract: ABSTRACT Previously, we reported that small ubiquitin-like modifier-1 (SUMO-1) promotes the degradation of a polyglutamine (polyQ) protein ataxin-3 and proposed that proteasomes mediate the proteolysis. Here, we present evidence that autophagy is also responsible for… read more here.
Keywords: protein; degradation; ataxin; sumo induced ... See more keywords