Abstract LB-319: Establishment of automated multiplex immunofluorescence T-cell panel for baseline screening of syngeneic mouse models and evaluation of T-cell infiltration in A20 syngeneic tumors treated with TAK-981, a first-in-class SUMO inhibitor
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DOI: 10.1158/1538-7445.am2019-lb-319
Abstract: Mouse syngeneic tumor models play a crucial role in the translationally oriented process of assessing the preclinical activity and mechanism of action of emerging novel immunotherapies and immunotherapy combinations. Recent advancements in fluorescent multiplex technology… read more here.
Keywords: sumo inhibitor; tak 981; syngeneic; mouse ... See more keywords