Post‐translational modifications of Arabidopsis E3 SUMO ligase AtSIZ1 are controlled by environmental conditions
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DOI: 10.1002/2211-5463.12309
Abstract: Sumoylation regulates numerous cellular functions in plants as well as in other eukaryotic systems. However, the regulatory mechanisms controlling E3 small ubiquitin‐related modifier (SUMO) ligase are not well understood. Here, post‐translational modification of the Arabidopsis… read more here.
Keywords: ligase atsiz1; sumo ligase; post translational; arabidopsis sumo ... See more keywords
A genome-wide screen of Epstein-Barr virus proteins that modulate host SUMOylation identifies a SUMO E3 ligase conserved in herpesviruses
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DOI: 10.1371/journal.ppat.1007176
Abstract: Many cellular processes pertinent for viral infection are regulated by the addition of small ubiquitin-like modifiers (SUMO) to key regulatory proteins, making SUMOylation an important mechanism by which viruses can commandeer cellular pathways. Epstein-Barr virus… read more here.
Keywords: sumoylation; epstein barr; ligase; sumo ligase ... See more keywords
The SUMO E3 ligase activity of ORF45 determines KSHV lytic replication
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DOI: 10.1371/journal.ppat.1010504
Abstract: RSK1, an essential cellular kinase for Kaposi’s sarcoma-associated herpesvirus (KSHV) replication, is highly phosphorylated and SUMOylated during KSHV lytic cycle, which determine the substrate phosphorylation and specificity of RSK1, respectively. However, the SUMO E3 ligase… read more here.
Keywords: rsk1; kshv lytic; replication; ligase ... See more keywords
Mms21: A Putative SUMO E3 Ligase in Candida albicans That Negatively Regulates Invasiveness and Filamentation, and Is Required for the Genotoxic and Cellular Stress Response
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DOI: 10.1534/genetics.118.301769
Abstract: In the life cycle of the fungal pathogen Candida albicans, the formation of filamentous cells is a differentiation process that is critically involved in host tissue invasion, and in adaptation to host cell and environmental… read more here.
Keywords: mms21; filamentation; sumo ligase; stress ... See more keywords