SUMO-specific protease 1 inhibitors–A literature and patent overview
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Therapeutic Patents"
DOI: 10.1080/13543776.2022.2165910
Abstract: ABSTRACT Introduction Cancer is currently one of the biggest killers threatening human health. More and more studies have confirmed that SUMO-specific protease 1 (SENP1) is over-expressed in various cancer tissues. Therefore, targeting SENP1 expression may… read more here.
Keywords: specific protease; sumo specific; inhibitors literature; protease inhibitors ... See more keywords
Rescuing p53 from mdm2 by a pre-structured motif in intrinsically unfolded SUMO specific protease 4
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DOI: 10.5483/bmbrep.2017.50.10.131
Abstract: Many intrinsically unstructured/unfolded proteins (IUPs) contain transient local secondary structures even though they are “unstructured” in a tertiary sense. These local secondary structures are named “pre-structured motifs (PreSMos)” and in fact are the specificity determinants… read more here.
Keywords: pre structured; specific protease; p53; p53 mdm2 ... See more keywords