A SUMO1-derived peptide targeting SUMO-interacting motif inhibits α-synuclein aggregation.
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DOI: 10.1016/j.chembiol.2020.12.010
Abstract: The accumulation of α-synuclein amyloid fibrils in the brain is linked to Parkinson's disease and other synucleinopathies. The intermediate species in the early aggregation phase of α-synuclein are involved in the emergence of amyloid toxicity… read more here.
Keywords: synuclein aggregation; aggregation; sumo1; sumo1 derived ... See more keywords