Regulated degradation of the inner nuclear membrane protein SUN2 maintains nuclear envelope architecture and function
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DOI: 10.1101/2022.07.15.500172
Abstract: Nuclear architecture and functions depend on dynamic interactions between nuclear components (such as chromatin) and inner nuclear membrane (INM) proteins. Mutations in INM proteins interfering with these interactions result in disease. However, mechanisms controlling the… read more here.
Keywords: inner nuclear; sun2; architecture; membrane ... See more keywords
Effects of Inner Nuclear Membrane Proteins SUN1/UNC-84A and SUN2/UNC-84B on the Early Steps of HIV-1 Infection
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DOI: 10.1128/jvi.00463-17
Abstract: ABSTRACT Human immunodeficiency virus type 1 (HIV-1) infection of dividing and nondividing cells involves regulatory interactions with the nuclear pore complex (NPC), followed by translocation to the nucleus and preferential integration into genomic areas in… read more here.
Keywords: hiv infection; infection; sun2; sun1 sun2 ... See more keywords
Loss of Sun2 promotes the progression of prostate cancer by regulating fatty acid oxidation
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19210
Abstract: The role of Sun2 has been described by previous studies in various types of cancers, including breast cancer and lung cancer. However, its role and potential molecular mechanism in the progression of prostate cancer have… read more here.
Keywords: prostate cancer; sun2; cancer; progression ... See more keywords