Superiority of living animal models in microsurgical training: beyond technical expertise
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Plastic Surgery"
DOI: 10.1007/s00238-021-01798-1
Abstract: Many studies are investigating the role of living and nonliving models to train microsurgeons. There is controversy around which modalities account for the best microsurgical training. In this study, we aim to provide a systematic… read more here.
Keywords: superiority; non technical; microsurgical training; living nonliving ... See more keywords
Methodological aspects of superiority, equivalence, and non-inferiority trials
Sign Up to like & getrecommendations! Published in 2020 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-020-02450-9
Abstract: Depending on the scientific hypothesis to be addressed, randomized-controlled trials (RCT) are accordingly designed. RCTs that aim to determine whether a novel, experimental therapeutic intervention (either a drug or a treatment) is superior to a… read more here.
Keywords: intervention; superiority; equivalence non; non inferiority ... See more keywords
Cognitive and neural markers of super-recognisers’ face processing superiority and enhanced cross-age effect
Sign Up to like & getrecommendations! Published in 2018 at "Cortex"
DOI: 10.1016/j.cortex.2018.07.008
Abstract: Super-recognisers inhabit the extreme high end of an adult face processing ability spectrum in the population. While almost all research in this area has evaluated those with poor or mid-range abilities, evaluating whether super-recognisers' superiority… read more here.
Keywords: superiority; cross age; age; recognition ... See more keywords
The effect of information superiority on a supply chain of virtual products
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Production Economics"
DOI: 10.1016/j.ijpe.2019.07.004
Abstract: Abstract Virtual products, such as mobile apps, 3D print files, e-music, etc., are produced with ample capacity and supplied with zero lead-time. We consider a two-echelon supply chain of a virtual product whose parties, a… read more here.
Keywords: retailer; manufacturer; information superiority; virtual products ... See more keywords
Is a filled lateral canal – A sign of superiority?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Dental Sciences"
DOI: 10.1016/j.jds.2020.02.009
Abstract: Three-dimensional disinfection is more important than three-dimensional obturation. This letter refreshes and re-emphasizes various concepts on filling lateral canals and apical ramifications. Several questions on the importance of filling these accessory innervations if any, beneficial… read more here.
Keywords: superiority; filling accessory; lateral canal; root canal ... See more keywords
Investigating superiority of novel bilosomes over niosomes in the transdermal delivery of diacerein: in vitro characterization, ex vivo permeation and in vivo skin deposition study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Liposome Research"
DOI: 10.1080/08982104.2018.1430831
Abstract: Abstract Skin is considered the most accessible organ of the body because of its underlying capillary network. However, stratum corneum (SC), the upper most layer of skin, represents major diffusional barrier for most drugs. Hence,… read more here.
Keywords: transdermal delivery; superiority; niosomes transdermal; novel bilosomes ... See more keywords
A confirmatory basket design considering non-inferiority and superiority testing.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biopharmaceutical statistics"
DOI: 10.1080/10543406.2023.2192781
Abstract: For multiple rare diseases as defined by a common biomarker signature, or a disease with multiple disease subtypes of low frequency, it is often possible to provide confirmatory evidence for these disease or subtypes (baskets)… read more here.
Keywords: inferiority; non inferiority; confirmatory basket; design ... See more keywords
A SYSTEMATIC REVIEW OF SUPERIORITY TRIALS TO ELUCIDATE THE CONCEPT OF SUPERIORITY MARGIN
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000571368.66685.36
Abstract: Objective:Progress towards superiority trial design and analysis has been slow. A statistically significant result may not be clinically relevant. In this study, we aimed to show that overpowered trials show statistical significance sans clinical relevance.Design… read more here.
Keywords: trials elucidate; elucidate concept; superiority trials; systematic review ... See more keywords
The inferiority of noninferiority trials
Sign Up to like & getrecommendations! Published in 2020 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.15592
Abstract: Noninferiority trials are increasingly popular in surgical literature. They aim to demonstrate that a new treatment is no worse than an existing treatment but may have added benefits. Their design is, in many ways, counterintuitive… read more here.
Keywords: intervention; superiority; null hypothesis; control ... See more keywords
Lenvatinib May Drastically Change the Treatment Landscape of Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Liver Cancer"
DOI: 10.1159/000487148
Abstract: Sorafenib, which was shown to improve survival in the SHARP [1] and Asia-Pacific [2] trials, has been the standard therapy for unresectable hepatocellular carcinoma (HCC) since 2007. Since then, several first-line clinical trials have been… read more here.
Keywords: hepatocellular carcinoma; superiority; trial; hcc ... See more keywords
Commentary on Bamat et al.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Trials"
DOI: 10.1177/1740774520941442
Abstract: This issue of Clinical Trials presents noteworthy insights into protocol adherence and hypothesis confirmation in non-inferiority randomized trials. Noninferiority trials usually compare two interventions with similar expected efficacy, but possible differences in convenience or cost.… read more here.
Keywords: superiority; inferiority trials; non inferiority; hypothesis ... See more keywords