Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Both Generate Superoxide/H2O2 in a Side Reaction and Each Could Contribute to Oxidative Stress in Mitochondria
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DOI: 10.1007/s11064-019-02765-w
Abstract: According to recent findings, the human 2-oxoglutarate dehydrogenase complex (hOGDHc) could be an important source of the reactive oxygen species in the mitochondria and could contribute to mitochondrial abnormalities associated with multiple neurodegenerative diseases, including… read more here.
Keywords: dehydrogenase; oxoglutarate dehydrogenase; could contribute; human oxoglutarate ... See more keywords