Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment
Sign Up to like & getrecommendations! Published in 2017 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2017.05.015
Abstract: &NA; Long‐term exposure to antipsychotics like haloperidol can increase sensitivity to dopamine agonist stimulation. This could contribute to treatment failure and increase relapse to psychosis. Chronic antipsychotic treatment elevates neurotensin levels in the nucleus accumbens… read more here.
Keywords: dopamine supersensitivity; treatment; neurotensin; hal ... See more keywords
Valbenazine and Deutetrabenazine as possible treatments for neuroleptic-induced supersensitivity psychosis and antipsychotic dependence
Sign Up to like & getrecommendations! Published in 2018 at "CNS Spectrums"
DOI: 10.1017/s1092852918001116
Abstract: Dear Editor, The article in the February 2018 issue of CNS Spectrums titled “Mechanism of action of vesicular monoamine transporter 2 (VMAT2) inhibitors in tardive dyskinesia” has thoroughly elucidated the mechanism of dysfunction in tardive… read more here.
Keywords: valbenazine deutetrabenazine; supersensitivity psychosis; treatment; supersensitivity ... See more keywords