A double-blind, randomized, placebo-controlled, pilot clinical trial examining buspirone as an adjunctive medication during buprenorphine-assisted supervised opioid withdrawal.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental and clinical psychopharmacology"
DOI: 10.1037/pha0000550
Abstract: Successful management of opioid withdrawal improves long-term treatment outcomes and reduces opioid use-related morbidity and mortality. Mechanistically supported pharmacotherapeutic approaches are needed to effectively manage acute and protracted opioid withdrawal. Buspirone is a D2 antagonist… read more here.
Keywords: supervised opioid; withdrawal; double blind; buspirone ... See more keywords
The effects of cytochrome P450 2D6 inhibitors on a high-dose tramadol taper for medically supervised opioid withdrawal: a retrospective chart review
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Addictive Diseases"
DOI: 10.1080/10550887.2020.1818912
Abstract: Abstract Background: Tramadol is used off-label for medically supervised opioid withdrawal. Tramadol is metabolized by CYP2D6 to an active metabolite with significantly more pharmacologic activity compared to the parent compound. Objectives: The objective of this… read more here.
Keywords: tramadol taper; opioid withdrawal; medically supervised; withdrawal ... See more keywords