Mechanistic Investigations Support Liver Safety of Ubrogepant
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DOI: 10.1093/toxsci/kfaa093
Abstract: Abstract Small-molecule calcitonin gene-related peptide (CGRP) receptor antagonists have demonstrated therapeutic efficacy for the treatment of migraine. However, previously investigated CGRP receptor antagonists, telcagepant and MK-3207, were discontinued during clinical development because of concerns about… read more here.
Keywords: cgrp receptor; telcagepant 3207; support liver; mechanistic investigations ... See more keywords
Nutritional support in liver disease – an updated systematic review
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DOI: 10.1097/mog.0000000000000914
Abstract: Purpose of review The association of malnutrition and a poor prognosis does not prove that providing nutrition support improves that prognosis. The proof of such efficacy requires its demonstration in well designed and executed randomized… read more here.
Keywords: review; support liver; systematic review; support ... See more keywords