Single-cell transcriptomic profiling of the zebrafish inner ear reveals molecularly distinct hair cell and supporting cell subtypes
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.09.08.507120
Abstract: A major cause of human deafness and vestibular dysfunction is permanent loss of the mechanosensory hair cells of the inner ear. In non-mammalian vertebrates such as zebrafish, regeneration of missing hair cells can occur throughout… read more here.
Keywords: cell; hair cell; inner ear; supporting cell ... See more keywords
Dibenzazepine promotes cochlear supporting cell proliferation and hair cell regeneration in neonatal mice
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DOI: 10.1111/cpr.12872
Abstract: To investigate the role of dibenzazepine (DBZ) in promoting supporting cell (SC) proliferation and hair cell (HC) regeneration in the inner ear. read more here.
Keywords: proliferation hair; hair cell; cell proliferation; supporting cell ... See more keywords
ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.14183
Abstract: In mammals, cochlear hair cells are not regenerated once they are lost, leading to permanent hearing deficits. In other vertebrates, the adjacent supporting cells act as a stem cell compartment, in that they both proliferate… read more here.
Keywords: hair cell; hair cells; hair; supporting cells ... See more keywords