PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.ade8641
Abstract: Phosphatidylinositol (PI)regulating enzymes are frequently altered in cancer and have become a focus for drug development. Here, we explore the phosphatidylinositol-5-phosphate 4-kinases (PI5P4K), a family of lipid kinases that regulate pools of intracellular PI, and… read more here.
Keywords: prostate cancer; androgen receptor; supports prostate; cancer ... See more keywords