Inhibition of Leukotriene A4 Hydrolase Suppressed Cartilage Degradation and Synovial Inflammation in a Mouse Model of Experimental Osteoarthritis.
Sign Up to like & getrecommendations! Published in 2022 at "Cartilage"
DOI: 10.21203/rs.3.rs-1245437/v1
Abstract: OBJECTIVE Chronic inflammation plays an important role in the osteoarthritis (OA) pathology but how this influence OA disease progression is unclear. Leukotriene B4 (LTB4) is a potent proinflammatory lipid mediator generated from arachidonic acid through… read more here.
Keywords: leukotriene hydrolase; inflammation; inhibition; cartilage ... See more keywords