Upstream stimulating factor 1 suppresses autophagy and hepatic lipid droplet catabolism by activating mTOR
Sign Up to like & getrecommendations! Published in 2018 at "Febs Letters"
DOI: 10.1002/1873-3468.13203
Abstract: Previous studies indicate that the transcription factor upstream stimulating factor 1 (USF1) is involved in the regulation of lipid and glucose metabolism. However, the role of USF1 in lipid‐induced autophagy remains unknown. Interestingly, we found… read more here.
Keywords: suppresses autophagy; stimulating factor; upstream stimulating; mtor ... See more keywords
Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15182
Abstract: Gene deletion-induced autophagy deficiency leads to neural tube defects (NTDs), similar to those in diabetic pregnancy. Here we report the key autophagy regulators modulated by diabetes in the murine developing neuroepithelium. Diabetes predominantly leads to… read more here.
Keywords: tube defects; diabetic pregnancy; suppresses autophagy; mir 129 ... See more keywords