PTEN suppresses axon outgrowth by down-regulating the level of detyrosinated microtubules
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DOI: 10.1371/journal.pone.0193257
Abstract: Inhibition of the phospholipid phosphatase and tumor suppressor PTEN leads to excessive polarized cell growth during directed cell migration and neurite outgrowth. These processes require the precise regulation of both the actin and microtubule cytoskeleton.… read more here.
Keywords: axon outgrowth; suppresses axon; pten suppresses; detyrosinated microtubules ... See more keywords