Activation of the mitogen‐activated protein kinase ERK1/2 signaling pathway suppresses the expression of ChREBPα and β in HepG2 cells
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DOI: 10.1002/2211-5463.13208
Abstract: The carbohydrate response element‐binding protein (ChREBP), a glucose‐responsive transcription factor that plays a critical role in the glucose‐mediated induction of genes involved in hepatic glycolysis and lipogenesis, exists as two isoforms: ChREBPα and ChREBPβ. However,… read more here.
Keywords: suppresses expression; expression chrebp; hepg2 cells; hepg2 ... See more keywords
Harpagoside suppresses IL‐6 expression in primary human osteoarthritis chondrocytes
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DOI: 10.1002/jor.23262
Abstract: There is growing evidence in support of the involvement of inflammatory response in the pathogenesis of osteoarthritis (OA). Harpagoside, one of the bioactive components of Harpagophytum procumbens (Hp), has been shown to possess anti‐inflammatory properties.… read more here.
Keywords: suppresses expression; harpagoside suppresses; osteoarthritis; chondrocytes harpagoside ... See more keywords