Antagonistic Insulin Derivative Suppresses Insulin-Induced Hypoglycemia.
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DOI: 10.1021/acs.jmedchem.3c00280
Abstract: Insulin derivatives provide new functions that are distinctive from native insulin. We investigated insulin modifications on the C-terminal A chain with insulin receptor (IR) peptide binders and presented a full and potent IR antagonist. We… read more here.
Keywords: insulin induced; insulin derivative; induced hypoglycemia; suppresses insulin ... See more keywords