Gambogic acid suppresses the pentose phosphate pathway by covalently inhibiting 6PGD protein in cancer cells.
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DOI: 10.1039/d2cc03069a
Abstract: Whether or not the anticancer activity of gambogic acid is achieved via regulating the cellular metabolic process remains unclear. Here we report that gambogic acid suppresses the pentose phosphate pathway (PPP) by covalently inhibiting the… read more here.
Keywords: suppresses pentose; phosphate pathway; acid suppresses; pentose phosphate ... See more keywords