Quercetin protects cardiomyocytes against doxorubicin-induced toxicity by suppressing oxidative stress and improving mitochondrial function via 14-3-3γ
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2018.1564948
Abstract: Abstract Cardiotoxicity limits the clinical applications of doxorubicin (Dox), which mechanism might be excess generation of intracellular ROS. Quercetin (Que) is a flavonoid that possesses anti-oxidative activities, exerts myocardial protection. We hypothesized that the cardioprotection… read more here.
Keywords: stress improving; induced toxicity; improving mitochondrial; suppressing oxidative ... See more keywords
8-Formylophiopogonanone B Antagonizes Paraquat-Induced Hepatotoxicity by Suppressing Oxidative Stress
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.01283
Abstract: Flavonoids are some of the most important natural products with a variety of physiological activities. 8-Formylophiopogonanone B (8-FOB) is a naturally existing homoisoflavonoid in Ophiopogon japonicus. Paraquat (PQ) has been widely used as a potent… read more here.
Keywords: suppressing oxidative; induced hepatotoxicity; paraquat; oxidative stress ... See more keywords
Increased expression of glutathione peroxidase 3 prevents tendinopathy by suppressing oxidative stress
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1137952
Abstract: Tendinopathy, a degenerative disease, is characterized by pain, loss of tendon strength, or rupture. Previous studies have identified multiple risk factors for tendinopathy, including aging and fluoroquinolone use; however, its therapeutic target remains unclear. We… read more here.
Keywords: increased expression; prevents tendinopathy; suppressing oxidative; glutathione peroxidase ... See more keywords