Effect of Androgen Suppression on Clinical Outcomes in Hospitalized Men With COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.7852
Abstract: Key Points Question Does androgen suppression improve clinical outcomes in hospitalized men with COVID-19? Findings In this randomized clinical trial including 96 men, androgen suppression with the addition of degarelix vs placebo plus standard care… read more here.
Keywords: clinical outcomes; outcomes hospitalized; hospitalized men; androgen suppression ... See more keywords
Factors Associated With Successful Discontinuation of Immune Suppression After Allogeneic Hematopoietic Cell Transplantation.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2019.2974
Abstract: Importance Immune suppression discontinuation is routinely attempted after allogeneic hematopoietic cell transplantation (HCT) and under current practices may lead to graft-vs-host disease (GVHD)-associated morbidity and death. However, the likelihood and predictive factors associated with successful… read more here.
Keywords: suppression; immune suppression; suppression discontinuation; factors associated ... See more keywords
MAPK‐Targeted Drug Delivered by a pH‐Sensitive MSNP Nanocarrier Synergizes with PD‐1 Blockade in Melanoma without T‐Cell Suppression
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201806916
Abstract: The combination of BRAF/MEK‐targeted therapy with immune checkpoint blockade is regarded as a promising regimen for patients with metastatic melanoma due to their complementary advantages. However, MEK‐inhibitor‐induced T‐cell toxicity impedes effective cooperation. In this experiment,… read more here.
Keywords: mapk targeted; mek inhibitor; suppression; inhibitor ... See more keywords
Mechanisms of suppression: The wiring of genetic resilience
Sign Up to like & getrecommendations! Published in 2017 at "BioEssays"
DOI: 10.1002/bies.201700042
Abstract: Recent analysis of genome sequences has identified individuals that are healthy despite carrying severe disease‐associated mutations. A possible explanation is that these individuals carry a second genomic perturbation that can compensate for the detrimental effects… read more here.
Keywords: suppression interactions; suppression; wiring genetic; mechanisms suppression ... See more keywords
Suppression of ABCD2 dysregulates lipid metabolism via dysregulation of miR‐141:ACSL4 in human osteoarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3356
Abstract: Even though increasing evidence indicates the importance of peroxisomal lipid metabolism in regulating biological and pathological events, its involvement in cartilage development has not been well studied. Here, we identified the importance of peroxisomal function,… read more here.
Keywords: suppression; metabolism; acsl4 human; osteoarthritis ... See more keywords
Experimental insect suppression causes loss of induced, but not constitutive, resistance in Solanum carolinense.
Sign Up to like & getrecommendations! Published in 2022 at "Ecology"
DOI: 10.1002/ecy.3786
Abstract: Spatiotemporal variation in herbivory is a major driver of intraspecific variation in plant defense. Comparatively little is known, however, about how changes in herbivory regime affect the balance of constitutive and induced resistance, which are… read more here.
Keywords: constitutive resistance; induced resistance; solanum carolinense; insect suppression ... See more keywords
Prolonged suppression of the anti‐oxidant/anti‐inflammatory effects of BNP post‐Takotsubo syndrome
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12729
Abstract: Takotsubo syndrome (TTS) episodes are primarily initiated by ‘pulse’ release of catecholamines inducing neutrophil infiltration and myocardial inflammation in susceptible individuals (largely ageing women). Evidence of myocardial inflammation and associated energetic impairment persists for ≥… read more here.
Keywords: suppression; anti oxidant; prolonged suppression; takotsubo syndrome ... See more keywords
Sequestration of 2,3,7,8-tetrachlorodibenzo-p-dioxin by activated carbon eliminates bioavailability and the suppression of immune function in mice.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.3815
Abstract: The effectiveness of activated carbon in reducing the bioavailability of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was examined from the context of using in situ sorbent amendments to remediate soils/sediments contaminated with polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs). This technology has gained… read more here.
Keywords: suppression; carbon; tcdd; bioavailability ... See more keywords
Evaluating the suppression effectiveness of hybrid nitrogen and water mist with a cup burner coflowing flame
Sign Up to like & getrecommendations! Published in 2021 at "Fire and Materials"
DOI: 10.1002/fam.2966
Abstract: The suppression effectiveness of an intrinsically clean hybrid fire suppressant consisting of nitrogen and water mist was experimentally studied by a cup burner method with methane/air coflowing flame. A series of hybrid agents with different… read more here.
Keywords: nitrogen water; suppression; water; mist ... See more keywords
Experimental suppression of transcranial magnetic stimulation‐electroencephalography sensory potentials
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.25990
Abstract: The sensory experience of transcranial magnetic stimulation (TMS) evokes cortical responses measured in electroencephalography (EEG) that confound interpretation of TMS‐evoked potentials (TEPs). Methods for sensory masking have been proposed to minimize sensory contributions to the… read more here.
Keywords: n100 p200; magnetic stimulation; vertex n100; suppression ... See more keywords
DACT3 has a tumor‐inhibiting role in acute myeloid leukemia via the suppression of Wnt/β‐catenin signaling by DVL2
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23014
Abstract: Dapper antagonist of catenin‐3 (DACT3) is a new tumor‐related protein associated with a diverse set of tumors. However, whether DACT3 plays a role in acute myeloid leukemia (AML) is not fully understood. Our findings showed… read more here.
Keywords: role; wnt catenin; catenin; suppression ... See more keywords