Licochalcone A attenuates acne symptoms mediated by suppression of NLRP3 inflammasome
Sign Up to like & getrecommendations! Published in 2018 at "Phytotherapy Research"
DOI: 10.1002/ptr.6195
Abstract: Activation of the NACHT, LRR and PYD domains‐containing protein 3 (NLRP3) inflammasome by Propionibacterium acnes (P. acnes) is critical for inducing inflammation and aggravating the development of acne lesions. We searched for available small‐molecule inhibitors… read more here.
Keywords: inflammasome licochalcone; licochalcone; nlrp3 inflammasome; acnes induced ... See more keywords
Safranal exerts a neuroprotective effect on Parkinson’s disease with suppression of NLRP3 inflammation activation
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Biology Reports"
DOI: 10.1007/s11033-024-09537-y
Abstract: Parkinson’s disease (PD) is a common central nervous system neurodegenerative disease. Neuroinflammation is one of the significant neuropathological hallmarks. As a traditional Chinese medicine, Safranal exerts anti-inflammatory effects in various diseases, however, whether it plays… read more here.
Keywords: disease; effect; suppression nlrp3; safranal exerts ... See more keywords