Circadian regulator CLOCK recruits immune suppressive microglia into the GBM tumor microenvironment.
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DOI: 10.1158/2159-8290.cd-19-0400
Abstract: Glioblastoma (GBM) is a lethal brain tumor containing a subpopulation of glioma stem cells (GSCs). Pan-cancer analyses have revealed that stemness of cancer cells correlates positively with immunosuppressive pathways in many solid tumors, including GBM,… read more here.
Keywords: immune suppressive; clock; suppressive microglia; tumor ... See more keywords