Targeting Suppressive Oligonucleotide to Lymph Nodes Inhibits Toll-like Receptor-9-Mediated Activation of Adaptive Immunity
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DOI: 10.1007/s11095-018-2344-2
Abstract: PurposeThis paper aims to investigate the immunoinhibitory properties of a lymph nodes-targeting suppressive oligonucleotide (ODN) for the potential treatment of autoimmune diseases or chronic inflammation.MethodsSynthetic suppressive ODN engineered with an albumin-binding diacyl lipid at the… read more here.
Keywords: suppressive odn; toll like; lymph nodes; suppressive oligonucleotide ... See more keywords