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   Articles with "suppressor" as a keyword



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High-throughput synthetic rescue for exhaustive characterization of suppressor mutations in human genes

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recommendations! Published in 2020 at "Cellular and Molecular Life Sciences"

DOI: 10.1007/s00018-020-03519-6

Abstract: Inherited or acquired mutations can lead to pathological outcomes. However, in a process defined as synthetic rescue, phenotypic outcome created by primary mutation is alleviated by suppressor mutations. An exhaustive characterization of these mutations in… read more here.

Keywords: exhaustive characterization; synthetic rescue; suppressor; suppressor mutations ... See more keywords

Predicting Subjective Well-Being from Personality: The Effects of Suppression, Confounding, and Mediating Variables

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recommendations! Published in 2025 at "Journal of Happiness Studies"

DOI: 10.1007/s10902-025-00859-7

Abstract: This article presents a study examining 1) how personality predicts subjective well-being (SWB) and the possible suppression and confounding effects, and 2) the mediating role of fruit and vegetable (FV) consumption. This article addresses the… read more here.

Keywords: consumption; personality; suppression confounding; subjective well ... See more keywords

Unique fertility restoration suppressor genes for male-sterile CMS ANN2 and CMS ANN3 cytoplasms in sunflower (Helianthus annuus L.)

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recommendations! Published in 2018 at "Molecular Breeding"

DOI: 10.1007/s11032-018-0922-y

Abstract: Single dominant fertility restoration (Rf) genes for cytoplasmic male-sterile (CMS) sunflower lines CMS ANN2 and CMS ANN3 were previously identified in three and five sources, respectively. However, expressions of the dominant Rf genes were suppressed when… read more here.

Keywords: cms; restoration; suppressor; ann2 cms ... See more keywords

Acoustic attenuation performance prediction and analysis of bladder style hydraulic noise suppressors

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recommendations! Published in 2018 at "Applied Acoustics"

DOI: 10.1016/j.apacoust.2018.01.005

Abstract: Abstract Based on the acoustic-structure coupling and plane wave theory, this paper proposes a method for predicting the acoustic attenuation performance (AAP) of in-line bladder style hydraulic noise suppressor (bladder suppressor) and investigates the influences… read more here.

Keywords: attenuation performance; bladder; suppressor; acoustic attenuation ... See more keywords
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Differential localization and roles of splice variants of rat suppressor of cancer cell invasion (SCAI) in neuronal cells.

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recommendations! Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.06.064

Abstract: Suppressor of cancer cell invasion (SCAI) is a suppressor of myocardin-related transcription factor (MRTF)-mediated transcription and cancer cell invasion. However, roles of SCAI in the brain and neuronal cells are not fully resolved. In this… read more here.

Keywords: scai; scai variants; suppressor; cell invasion ... See more keywords

CCR6 signaling inhibits suppressor function of induced-Treg during gut inflammation.

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recommendations! Published in 2018 at "Journal of autoimmunity"

DOI: 10.1016/j.jaut.2017.10.013

Abstract: CCR6 is a G protein-coupled receptor (GPCR) that binds to a specific chemokine, CCL20. The role of CCR6-CCL20 is very well studied in the migration of immune cells, but the non-chemotaxis functions of CCR6 signaling… read more here.

Keywords: induced treg; gut inflammation; ccr6; ccr6 signaling ... See more keywords

Identification of Strawberry vein banding virus encoded P6 as an RNA silencing suppressor.

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recommendations! Published in 2018 at "Virology"

DOI: 10.1016/j.virol.2018.05.003

Abstract: RNA silencing is a common mechanism that plays a key role in antiviral defense. To overcome host defense responses, plant viruses encode silencing-suppressor proteins to target one or several key steps in the silencing machinery.… read more here.

Keywords: protein; rna silencing; silencing suppressor; suppressor ... See more keywords

Natural and Synthetic Suppressor Mutations Defy Stability–Activity Tradeoffs

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recommendations! Published in 2022 at "Biochemistry"

DOI: 10.1021/acs.biochem.1c00805

Abstract: Thermodynamic stability represents one important constraint on protein evolution, but the molecular basis for how mutations that change stability impact fitness remains unclear. Here, we demonstrate that a prevalent global suppressor mutation in TEM β-lactamase,… read more here.

Keywords: suppressor; natural synthetic; stability; stability activity ... See more keywords

Scan-Find-Scan-Model: Discrete Site-Targeted Suppressor Design Strategy for Amyloid-β.

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recommendations! Published in 2022 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.2c00272

Abstract: Alzheimer's disease is undoubtedly the most well-studied neurodegenerative disease. Consequently, the amyloid-β (Aβ) protein ranks at the top in terms of getting attention from the scientific community for structural property-based characterization. Even after decades of… read more here.

Keywords: suppressor; site; target sequence; scan find ... See more keywords

The true role that suppressor effects play in condition-based regression analysis: None. A reply to Fiedler (2021).

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recommendations! Published in 2022 at "Journal of personality and social psychology"

DOI: 10.1037/pspp0000428

Abstract: Condition-based regression analysis (CRA) is a statistical method for testing self-enhancement effects. That is, CRA indicates whether, in a set of empirical data, people with higher values on the directed discrepancy self-view S minus reality… read more here.

Keywords: regression analysis; fiedler 2021; condition based; suppressor ... See more keywords

p53 target ANKRA2 cooperates with RFX7 to regulate tumor suppressor genes

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recommendations! Published in 2024 at "Cell Death Discovery"

DOI: 10.1038/s41420-024-02149-2

Abstract: The transcription factor regulatory factor X 7 (RFX7) has been identified as a tumor suppressor that is recurrently mutated in lymphoid cancers and appears to be dysregulated in many other cancers. RFX7 is activated by… read more here.

Keywords: ankra2; suppressor genes; tumor suppressor; p53 target ... See more keywords