Cysteine oxidation triggers amyloid fibril formation of the tumor suppressor p16INK4A
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DOI: 10.1016/j.redox.2019.101316
Abstract: The tumor suppressor p16INK4A induces cell cycle arrest and senescence in response to oncogenic transformation and is therefore frequently lost in cancer. p16INK4A is also known to accumulate under conditions of oxidative stress. Thus, we… read more here.
Keywords: p16ink4a; suppressor p16ink4a; oxidation; cysteine ... See more keywords