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Published in 2019 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2019.113473
Abstract: Cancer is a general word, which specifies a cluster of diseases affecting almost every-body part. Cancer is a second leading cause of death, globally. The tumor suppressor protein p53 is known to play a vital…
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Keywords:
protein;
tumor suppressor;
suppressor protein;
cancer ... See more keywords
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Published in 2017 at "Cell Reports"
DOI: 10.1016/j.celrep.2017.05.053
Abstract: Summary The retinoblastoma tumor suppressor protein pRb is a master regulator of cellular proliferation, principally through interaction with E2F and regulation of E2F target genes. Here, we describe the H1.2 linker histone as a major…
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Keywords:
target genes;
tumor suppressor;
prb;
suppressor protein ... See more keywords
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Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00121
Abstract: Nucleoside diphosphate kinases (Nmes or NDPKs) have been implicated in a multitude of cellular processes, including an important role in metastasis suppression, and several enzymatic activities have been assigned to the Nme family. Nevertheless, for…
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Keywords:
protein;
suppressor protein;
metastasis suppressor;
calmodulin dependent ... See more keywords
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Published in 2017 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.dnarepair16-a39
Abstract: The DAB2IP tumor suppressor protein is a member of the Ras GTPase-activating protein family and is often downregulated by epigenetic silencing in many advanced cancer types. Current literature indicates that DAB2IP plays a crucial role…
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Keywords:
spindle assembly;
tumor suppressor;
dab2ip;
suppressor protein ... See more keywords
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1
Published in 2018 at "Biology Open"
DOI: 10.1242/bio.033985
Abstract: ABSTRACT The tumor suppressor protein RECK has been implicated in the regulation of matrix metalloproteinases (MMPs), NOTCH-signaling and WNT7-signaling. It remains unclear, however, how broad the spectrum of RECK targets extends. To find novel RECK…
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Keywords:
tumor suppressor;
reck;
suppressor protein;