Articles with "suppressor protein" as a keyword



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Detection of tumor suppressor protein p53 with special emphasis on biosensors: A review.

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Published in 2019 at "Analytical biochemistry"

DOI: 10.1016/j.ab.2019.113473

Abstract: Cancer is a general word, which specifies a cluster of diseases affecting almost every-body part. Cancer is a second leading cause of death, globally. The tumor suppressor protein p53 is known to play a vital… read more here.

Keywords: protein; tumor suppressor; suppressor protein; cancer ... See more keywords
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Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates Its Function

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Published in 2017 at "Cell Reports"

DOI: 10.1016/j.celrep.2017.05.053

Abstract: Summary The retinoblastoma tumor suppressor protein pRb is a master regulator of cellular proliferation, principally through interaction with E2F and regulation of E2F target genes. Here, we describe the H1.2 linker histone as a major… read more here.

Keywords: target genes; tumor suppressor; prb; suppressor protein ... See more keywords
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The Metastasis Suppressor Protein Nme1 Is a Concentration-Dependent Modulator of Ca2+/Calmodulin-Dependent Protein Kinase II.

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Published in 2019 at "Biochemistry"

DOI: 10.1021/acs.biochem.9b00121

Abstract: Nucleoside diphosphate kinases (Nmes or NDPKs) have been implicated in a multitude of cellular processes, including an important role in metastasis suppression, and several enzymatic activities have been assigned to the Nme family. Nevertheless, for… read more here.

Keywords: protein; suppressor protein; metastasis suppressor; calmodulin dependent ... See more keywords
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Abstract A39: Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetorchore-microtubule attachments

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Published in 2017 at "Molecular Cancer Research"

DOI: 10.1158/1557-3125.dnarepair16-a39

Abstract: The DAB2IP tumor suppressor protein is a member of the Ras GTPase-activating protein family and is often downregulated by epigenetic silencing in many advanced cancer types. Current literature indicates that DAB2IP plays a crucial role… read more here.

Keywords: spindle assembly; tumor suppressor; dab2ip; suppressor protein ... See more keywords
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The RECK tumor-suppressor protein binds and stabilizes ADAMTS10

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Published in 2018 at "Biology Open"

DOI: 10.1242/bio.033985

Abstract: ABSTRACT The tumor suppressor protein RECK has been implicated in the regulation of matrix metalloproteinases (MMPs), NOTCH-signaling and WNT7-signaling. It remains unclear, however, how broad the spectrum of RECK targets extends. To find novel RECK… read more here.

Keywords: tumor suppressor; reck; suppressor protein;