Supramolecular nanoprodrug based on a chloride channel blocker and glycosylated pillar[5]arenes for targeted chemoresistance cancer therapy.
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DOI: 10.1039/d3cc00233k
Abstract: A supramolecular nanoprodrug (DOX@GP5⊃Pro-NFA) was constructed based on the host-guest complexation of chloride channel blocker prodrug (Pro-NFA) and glycosylated pillar[5]arene (GP5), which could target tumor cells via galactose and release DOX/NFA responsively under esterase stimulation.… read more here.
Keywords: supramolecular nanoprodrug; channel blocker; chloride channel; glycosylated pillar ... See more keywords