Phenotype of a transient neonatal diabetes point mutation (SUR1-R1183W) in mice
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DOI: 10.12688/wellcomeopenres.15529.2
Abstract: Background: The K ATP channel plays a key role in glucose homeostasis by coupling metabolically generated changes in ATP to insulin secretion from pancreatic beta-cells. Gain-of-function mutations in either the pore-forming (Kir6.2) or regulatory (SUR1)… read more here.
Keywords: phenotype; sur1; mice; sur1 r1183w ... See more keywords