Beyond immune escape: a variant surface glycoprotein causes suramin resistance in Trypanosoma brucei
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DOI: 10.1111/mmi.13854
Abstract: Suramin is one of the first drugs developed in a medicinal chemistry program (Bayer, 1916), and it is still the treatment of choice for the hemolymphatic stage of African sleeping sickness caused by Trypanosoma brucei… read more here.
Keywords: surface glycoprotein; variant surface; trypanosoma brucei; suramin resistance ... See more keywords