Biomarkers of Acute Graft-Versus-Host Disease: Surface Antigens and Micro Rnas in Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.223
Abstract: Introduction Biomarkers could be crucial to identify patients at high-risk of acute Graft-vs.-Host Disease (aGVHD). Given their involvement in inflammation, Extracellular Vesicles (EVs) may become attractive biomarkers. Moreover, EVs are non-invasively extracted from body fluids.… read more here.
Keywords: cell adhesion; host disease; surface antigens; adhesion molecule ... See more keywords
Practical issues in measuring autoantibodies to neuronal cell-surface antigens in autoimmune neurological disorders: 190 cases
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2018.04.009
Abstract: OBJECTIVES To address practical issues in measuring autoantibodies to neuronal cell-surface antigens (NSAs) in various autoimmune neurological disorders (ANDs). METHODS We retrospectively reviewed the clinical information of 221 patients with clinically suspected ANDs who underwent… read more here.
Keywords: receptor; cell surface; practical issues; surface antigens ... See more keywords
Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-14655-9
Abstract: Lipopolysaccharide (LPS) O-antigen (O-Ag) is known to limit antibody binding to surface antigens, although the relationship between antibody, O-Ag and other outer-membrane antigens is poorly understood. Here we report, immunization with the trimeric porin OmpD… read more here.
Keywords: surface; antibody; outer membrane; lps antigen ... See more keywords
Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma
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DOI: 10.1038/s41598-024-56684-0
Abstract: Despite advancements in cancer immunotherapy, solid tumors remain formidable challenges. In glioma, profound inter- and intra-tumoral heterogeneity of antigen landscape hampers therapeutic development. Therefore, it is critical to consider alternative sources to expand the repertoire… read more here.
Keywords: alternative splicing; cell surface; specific alternative; surface antigens ... See more keywords
Designed protein logic to target cells with precise combinations of surface antigens
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.aba6527
Abstract: Logic at the cell surface A major challenge in medical interventions is to target only diseased cells. Although there are biomarkers characteristic of certain cancers, for example, it is unlikely that a single marker can… read more here.
Keywords: surface; surface antigens; cell surface; cell ... See more keywords
Abstract P61: SURFACEOME PROFILING TO IDENTIFY TARGETABLE CELL SURFACE ANTIGENS IN SOFT TISSUE SARCOMAS
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DOI: 10.1158/1538-7445.fcs2024-p61
Abstract: Soft tissue sarcomas (STS) represent rare cancers originating from mesenchymal tissues, featuring over 70 histological subtypes with diverse genetic defects and clinical outcomes. Current treatment options for STS mainly involve surgical procedures and anthracycline-based chemotherapy,… read more here.
Keywords: cell surface; surface antigens; cell; tissue sarcomas ... See more keywords
Treatment of Schistosoma mansoni with miltefosine in vitro enhances serological recognition of defined worm surface antigens
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0005853
Abstract: Background Miltefosine, an anti-cancer drug that has been successfully repositioned for treatment of Leishmania infections, has recently also shown promising effects against Schistosoma spp targeting all life cycle stages of the parasite. The current study… read more here.
Keywords: treatment; surface; worm surface; miltefosine ... See more keywords
A recombinant human immunoglobulin with coherent avidity to hepatitis B virus surface antigens of various viral genotypes and clinical mutants
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DOI: 10.1371/journal.pone.0236704
Abstract: The hepatitis B virus (HBV) envelope is composed of a lipid bilayer and three glycoproteins, referred to as the large (L), middle (M), and small (S) hepatitis B virus surface antigens (HBsAg). S protein constitutes… read more here.
Keywords: virus surface; hepatitis; antibody; surface antigens ... See more keywords
Standardization of Workflow and Flow Cytometry Panels for Quantitative Expression Profiling of Surface Antigens on Blood Leukocyte Subsets: An HCDM CDMaps Initiative
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.827898
Abstract: Background The Human Cell Differentiation Molecules (HCDM) organizes Human Leukocyte Differentiation Antigen (HLDA) workshops to test and name clusters of antibodies that react with a specific antigen. These cluster of differentiation (CD) markers have provided… read more here.
Keywords: quantitative expression; expression; profiling surface; leukocyte subsets ... See more keywords
Identification of Bacterial Surface Antigens by Screening Peptide Phage Libraries Using Whole Bacteria Cell-Purified Antisera
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.00082
Abstract: Bacterial surface proteins can be good vaccine candidates. In the present study, we used polyclonal antibodies purified with intact Erysipelothrix rhusiopthiae to screen phage-displayed random dodecapeptide and loop-constrained heptapeptide libraries, which led to the identification… read more here.
Keywords: using whole; phage; surface; surface antigens ... See more keywords
A Novel Methodology for Detecting Variations in Cell Surface Antigens Using Cell-Tearing by Optical Tweezers
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DOI: 10.3390/bios12080656
Abstract: The quantitative analysis of cell surface antigens has attracted increasing attention due to the antigenic variation recognition that can facilitate early diagnoses. This paper presents a novel methodology based on the optical “cell-tearing” and the… read more here.
Keywords: cell; surface antigens; methodology; cell surface ... See more keywords