Rapid Turnover of the Cardiac L-Type CaV1.2 Channel by Endocytic Recycling Regulates Its Cell Surface Availability
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DOI: 10.1016/j.isci.2018.08.012
Abstract: Summary Calcium entry through CaV1.2 L-type calcium channels regulates cardiac contractility. Here, we study the impact of exocytic and post-endocytic trafficking on cell surface channel abundance in cardiomyocytes. Single-molecule localization and confocal microscopy reveal an… read more here.
Keywords: endocytic recycling; channel; cav1; surface availability ... See more keywords