Tryptic shaving of Staphylococcus aureus unveils immunodominant epitopes on the bacterial cell surface.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.0c00043
Abstract: The opportunistic pathogen Staphylococcus aureus has become a major threat for human health and well-being by developing resistance to antibiotics, and by fast evolution into new lineages that rapidly spread within the healthy human population.… read more here.
Keywords: staphylococcus aureus; surface exposed; surface; cell surface ... See more keywords
Monoclonal Antibodies Targeting Surface-Exposed Epitopes of Candida albicans Cell Wall Proteins Confer In Vivo Protection in an Infection Model
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01957-21
Abstract: Monoclonal antibody (mAb)-based immunotherapies targeting systemic and deep-seated fungal infections are still in their early stages of development, with no licensed antifungal mAbs currently being available for patients at risk. The cell wall glycoproteins of… read more here.
Keywords: surface exposed; wall proteins; cell wall; candida albicans ... See more keywords
Catecholamine-Modulated Novel Surface-Exposed Adhesin LIC20035 of Leptospira spp. Binds Host Extracellular Matrix Components and Is Recognized by the Host during Infection
Sign Up to like & getrecommendations! Published in 2017 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.02360-17
Abstract: ABSTRACT In this study, the effect of the host stress hormone catecholamine on Leptospira gene transcripts encoding outer membrane proteins was investigated. There was no impact of catecholamine supplementation on the in vitro growth pattern… read more here.
Keywords: surface exposed; lic20035; host extracellular; leptospira ... See more keywords
Charge Fluctuations on a Dielectric Surface Exposed to Plasma Flows or UV Radiation
Sign Up to like & getrecommendations! Published in 2018 at "Plasma Physics Reports"
DOI: 10.1134/s1063780x18110089
Abstract: It is shown that fluctuating charge spots and local electric fields of up to 106 V/m and higher can form on a dielectric surface exposed to charged particle flows. A stochastic differential equation describing the… read more here.
Keywords: fluctuations dielectric; charge fluctuations; surface exposed; dielectric surface ... See more keywords
Labeling Strategies for Surface-Exposed Protein Visualization and Determination in Plasmodium falciparum Malaria
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.914297
Abstract: Malaria disease kills > 400,000 people every year, and Plasmodium falciparum is the causative agent of this severe disease (World Health Organization, 2021). The P. falciparum has a complex life cycle involving sexual reproduction in… read more here.
Keywords: plasmodium falciparum; surface exposed; determination; falciparum ... See more keywords
A Novel Pan-Genome Reverse Vaccinology Approach Employing a Negative-Selection Strategy for Screening Surface-Exposed Antigens against leptospirosis
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.00396
Abstract: Reverse vaccinology (RV) has been widely used for screening of surface-exposed proteins (PSEs) of important pathogens, including outer membrane proteins (OMPs), and extracellular proteins (ECPs) as potential vaccine candidates. In this study, we applied a… read more here.
Keywords: surface exposed; pan genome; strategy; screening surface ... See more keywords
Screening of Surface-Exposed Lipoproteins of Leptospira Involved in Modulation of Host Innate Immune Response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.761670
Abstract: Leptospira, a zoonotic pathogen, is capable of causing both chronic and acute infection in a susceptible host. Surface-exposed lipoproteins play a major role in modulating the host immune response by activating the innate cells like… read more here.
Keywords: surface exposed; surface; exposed lipoproteins; innate immune ... See more keywords
A Palette of Fluorescent Aβ42 Peptides Labelled at a Range of Surface-Exposed Sites
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031655
Abstract: Fluorescence-based single molecule techniques provide important tools towards understanding the molecular mechanism of complex neurodegenerative diseases. This requires efficient covalent attachment of fluorophores. Here we create a series of cysteine mutants (S8C, Y10C, S26C, V40C,… read more here.
Keywords: surface exposed; surface; palette fluorescent; form fibrils ... See more keywords
Structure of the Yeast Cell Wall Integrity Sensor Wsc1 Reveals an Essential Role of Surface-Exposed Aromatic Clusters
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8040379
Abstract: In the yeast Saccharomyces cerevisiae and other ascomycetes, the maintenance of cell wall integrity is governed by a family of plasma-membrane spanning sensors that include the Wsc-type proteins. These cell wall proteins apparently sense stress-induced… read more here.
Keywords: surface exposed; cell wall; wall integrity; exposed aromatic ... See more keywords
Borrelia burgdorferi Surface Exposed GroEL Is a Multifunctional Protein
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens"
DOI: 10.3390/pathogens10020226
Abstract: The spirochete, Borrelia burgdorferi, has a large number of membrane proteins involved in a complex life cycle, that includes a tick vector and a vertebrate host. Some of these proteins also serve different roles in… read more here.
Keywords: protein; surface exposed; exposed groel; groel ... See more keywords
Effect of Vacuum Annealing on the Compositions of U-0.79wt%Ti Alloy Surface Exposed in a Salt Fog Environment
Sign Up to like & getrecommendations! Published in 2017 at "Corrosion"
DOI: 10.5006/2315
Abstract: The evolution of the compositions in two typical regions on U-0.79wt%Ti alloy surface exposed in a salt fog environment was investigated by x-ray photoelectron spectroscopy (XPS) during vacuum annealing. The results show that pitting corrosion… read more here.
Keywords: surface exposed; alloy surface; surface; exposed salt ... See more keywords