A new protocol for long‐term culture of a specific subpopulation of liver cancer stem cells enriched by cell surface markers
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12932
Abstract: Liver cancer stem cells (L‐CSCs) are considered to be an important therapeutic target for hepatocellular carcinoma (HCC). This study provides a new in vitro long‐term culture model for a specific subpopulation of L‐CSCs enriched by… read more here.
Keywords: long term; cancer stem; surface markers;
T‐Cell Immunopeptidomes Reveal Cell Subtype Surface Markers Derived From Intracellular Proteins
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700410
Abstract: Immunopeptidomes promise novel surface markers as ideal immunotherapy targets, but their characterization by mass spectrometry (MS) remains challenging. Until recently, cell numbers exceeding 109 were needed to survey thousands of HLA ligands. Such limited analytical… read more here.
Keywords: cell immunopeptidomes; immunopeptidomes reveal; surface markers; hla ligands ... See more keywords
CD81 and CD117 Surface Markers Profiling of Prostate Cancer Urinary Exosomes Using CD9 Magnetic Beads
Sign Up to like & getrecommendations! Published in 2017 at "BioNanoScience"
DOI: 10.1007/s12668-016-0333-7
Abstract: Prostate cancer is one of leading cancers in men. While some types of prostate cancer grow slowly and may need minimal or no treatment, other types are aggressive and can spread quickly. The markers capable… read more here.
Keywords: cd81 cd117; prostate cancer; cd117 surface; surface markers ... See more keywords
A candidate triple-negative breast cancer vaccine design by targeting clinically relevant cell surface markers: an integrated immuno and bio-informatics approach
Sign Up to like & getrecommendations! Published in 2022 at "3 Biotech"
DOI: 10.1007/s13205-022-03140-3
Abstract: Triple-negative breast cancer (TNBC) is an aggressive, metastatic/invasive sub-class of breast cancer (BCa). Cell surface protein-derived multi-epitope vaccine-mediated targeting of TNBC cells could be a better strategy against the disease. Literature-based identified potential cell surface… read more here.
Keywords: cell surface; breast cancer; vaccine; surface markers ... See more keywords
ALDH1A1+ ovarian cancer stem cells co-expressing surface markers CD24, EPHA1 and CD9 form tumours in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112009
Abstract: One of the reasons for recurrence following treatment of high grade serous ovarian carcinoma (HGSOC) is the persistence of residual cancer stem cells (CSCs). There has been variability between laboratories in the identification of CSC… read more here.
Keywords: surface; ovarian cancer; surface markers; cell ... See more keywords
Using Electrochemical Immunoassay in a Novel Microtiter Plate to Detect Surface Markers of Preeclampsia on Urinary Extracellular Vesicles.
Sign Up to like & getrecommendations! Published in 2022 at "ACS sensors"
DOI: 10.1021/acssensors.2c02077
Abstract: Extracellular vesicles (EVs) are lipid bilayer nanovesicles secreted by cells. EVs contain biological information related to parental cells and provide biomarkers for disease diagnosis. We have previously shown that the levels of podocin and nephrin… read more here.
Keywords: microtiter plate; extracellular vesicles; novel microtiter; plate ... See more keywords
Rapid Assessment of Surface Markers on Cancer Cells Using Immuno-Magnetic Separation and Multi-frequency Impedance Cytometry for Targeted Therapy
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-57540-7
Abstract: The rapid qualitative assessment of surface markers on cancer cells can allow for point-of-care prediction of patient response to various cancer drugs. Preclinical studies targeting cells with an antibody to “activated” matriptase conjugated to a… read more here.
Keywords: frequency; cancer cells; surface markers; impedance ... See more keywords
QSurface: fast identification of surface expression markers in cancers
Sign Up to like & getrecommendations! Published in 2018 at "BMC Systems Biology"
DOI: 10.1186/s12918-018-0541-6
Abstract: BackgroundCell surface proteins have provided useful targets and biomarkers for advanced cancer therapies. The recent clinical success of antibody-drug conjugates (ADCs) highlights the importance of finding selective surface antigens for given cancer subtypes. We thus… read more here.
Keywords: expression markers; surface; expression; surface markers ... See more keywords
Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state
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DOI: 10.1186/s12931-018-0777-0
Abstract: Alveolar macrophages (AM) are critical to the homeostasis of the inflammatory environment in the lung. Differential expression of surface markers classifies macrophages to either classically (M1) or alternatively activated (M2). We investigated the phenotype of… read more here.
Keywords: alveolar macrophages; human alveolar; surface markers; macrophages predominately ... See more keywords
Predicting spinal column profile from surface topography via 3D non-contact surface scanning
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DOI: 10.1371/journal.pone.0282634
Abstract: Introduction 3D Non-Contact surface scanning (3DSS) is used in both biomechanical and clinical studies to capture accurate 3D images of the human torso, and to better understand the shape and posture of the spine–both healthy… read more here.
Keywords: external spine; topography; surface; surface markers ... See more keywords
Ectonucleotidases in Blood Malignancies: A Tale of Surface Markers and Therapeutic Targets
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02301
Abstract: Leukemia develops as the result of intrinsic features of the transformed cell, such as gene mutations and derived oncogenic signaling, and extrinsic factors, such as a tumor-friendly, immunosuppressed microenvironment, predominantly in the lymph nodes and… read more here.
Keywords: tale surface; markers therapeutic; surface markers; ectonucleotidases blood ... See more keywords