Lipid Monolayer on Cell Surface Protein Templates Functional Extracellular Lipid Assembly.
Sign Up to like & getrecommendations! Published in 2024 at "Small"
DOI: 10.1002/smll.202307793
Abstract: When the ancestors of men moved from aquatic habitats to the drylands, their evolutionary strategy to restrict water loss is to seal the skin surface with lipids. It is unknown how these rigid ceramide-dominated lipids… read more here.
Keywords: cell surface; templates functional; protein templates; surface ... See more keywords
Mapping Changes in Cell Surface Protein Expression Through Selective Labeling of Live Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7634-8_8
Abstract: ncRNAs are key players in the adaptation of bacteria to new environments, by modulating the composition of the membrane upon changes in the environment. Nevertheless, monitoring the changes in surface protein expression is still a… read more here.
Keywords: protein; protein expression; mapping changes; surface protein ... See more keywords
Protection elicited by nasal immunization with pneumococcal surface protein A (PspA) adjuvanted with bacterium-like particles against Streptococcus pneumoniae infection in mice.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2018.06.041
Abstract: Streptococcus pneumoniae is a major respiratory tract pathogen causing high levels of mortality and morbidity in infants and the elderly. In spite of the multitude of capsular polysaccharide vaccines used to guard against pneumococcal disease,… read more here.
Keywords: infection; immunization; surface protein; pspa ... See more keywords
Glycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.2c00332
Abstract: Driven by the lack of targeted therapies, triple negative breast cancers (TNBC) have the worst overall survival of all breast cancer subtypes. Considering cell surface proteins are favorable drug targets and are predominantly glycosylated, glycoproteome… read more here.
Keywords: cell; cell surface; growth invasion; surface ... See more keywords
Scratching the Surface of the Protein Corona: Challenging Measurements and Controversies.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c05901
Abstract: This Review aims to provide a systematic analysis of the literature regarding ongoing debates in protein corona research. Our goal is to portray the current understanding of two fundamental and debated characteristics of the protein… read more here.
Keywords: corona challenging; scratching surface; surface protein; challenging measurements ... See more keywords
Caspase-4 activation by a bacterial surface protein is mediated by cathepsin G in human gingival fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "Cell Death and Differentiation"
DOI: 10.1038/cdd.2017.167
Abstract: Caspase-4 is an inflammatory caspase; however, its mechanism of activation is poorly understood. In this study, we demonstrate that Td92, a surface protein of the periodontal pathogen Treponema denticola and a homolog of the Treponema… read more here.
Keywords: caspase activation; surface protein; td92; activation ... See more keywords
A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09955-8
Abstract: Ubiquitin-mediated xenophagy, a type of selective autophagy, plays crucial roles in host defense against intracellular pathogens including Mycobacterium tuberculosis (Mtb). However, the exact mechanism by which host ubiquitin targets invaded microbes to trigger xenophagy remains… read more here.
Keywords: mycobacterium tuberculosis; surface protein; host; xenophagy ... See more keywords
Pneumococcal surface protein A (PspA) prevents killing of Streptococcus pneumoniae by indolicidin
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-73564-9
Abstract: Pneumococcal surface protein A (PspA) is an important virulence factor in Streptococcus pneumoniae that binds to lactoferrin and protects the bacterium from the bactericidal action of lactoferricins—cationic peptides released upon lactoferrin proteolysis. The present study… read more here.
Keywords: indolicidin; pspa; pneumococcal surface; surface protein ... See more keywords
Association Between Pneumococcal Surface Protein A Family and Genetic/Antimicrobial Resistance Traits of Non-Invasive Pneumococcal Isolates from Adults in Northern Japan.
Sign Up to like & getrecommendations! Published in 2019 at "Microbial drug resistance"
DOI: 10.1089/mdr.2018.0267
Abstract: Pneumococcal isolates from adult patients in northern Japan in 2016 were subjected to molecular investigation related to pneumococcal surface protein A (PspA) and drug resistance determinants. Of the 51 isolates, serotype 3/ST180 was the most… read more here.
Keywords: pneumococcal surface; pneumococcal isolates; family; resistance ... See more keywords
Expression, immunogenicity and variation of iron‐regulated surface protein A from bovine isolates of Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2017 at "FEMS Microbiology Letters"
DOI: 10.1093/femsle/fnx082
Abstract: Abstract Staphylococcus aureus iron‐regulated surface protein A (IsdA) is a fibrinogen and fibronectin adhesin that also contributes to iron sequestration and resistance to innate immunity. IsdA is conserved in human isolates and has been investigated… read more here.
Keywords: isda; staphylococcus aureus; regulated surface; iron regulated ... See more keywords
Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Microbiology"
DOI: 10.1111/cmi.12786
Abstract: Borrelia burgdorferi (Bb) is the causative agent of Lyme disease in the United States, a disease that can result in carditis, and chronic and debilitating arthritis and/or neurologic symptoms if left untreated. Bb survives in… read more here.
Keywords: protein; outer surface; protein ospc; c4b ... See more keywords