Identification of Tumor‐Specific Surface Proteins Enables Quantification of Extracellular Vesicle Subtypes for Early Detection of Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202414982
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer‐related mortality, largely due to late‐stage diagnosis. Reliable early detection methods are critically needed. PDAC‐derived extracellular vesicles (EVs) carry molecules that reflect their parental tumor cells… read more here.
Keywords: early detection; surface; surface proteins; pdac ... See more keywords
Preclinical development of a novel Group B Streptococcus (GBS) vaccine candidate for maternal immunization based upon the alpha‐like protein family of GBS surface proteins (Alp)
Sign Up to like & getrecommendations! Published in 2023 at "Birth Defects Research"
DOI: 10.1002/bdr2.2173
Abstract: A novel Group B Streptococcus (GBS) vaccine, based upon the GBS alpha‐like surface proteins, is being developed by MinervaX for administration to pregnant women. The vaccine is intended to generate antibodies (IgG) capable of crossing… read more here.
Keywords: vaccine candidate; gbs; vaccine; surface proteins ... See more keywords
Melanin depletion affects Aspergillus flavus conidial surface proteins, architecture, and virulence
Sign Up to like & getrecommendations! Published in 2024 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-024-13107-4
Abstract: Abstract Melanin is an Aspergillus flavus cell wall component that provides chemical and physical protection to the organism. However, the molecular and biological mechanisms modulating melanin-mediated host–pathogen interaction in A. flavus keratitis are not well… read more here.
Keywords: melanin; conidial surface; virulence; surface ... See more keywords
Novel processes to obtain pneumococcal surface proteins for vaccines
Sign Up to like & getrecommendations! Published in 2025 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-025-13440-2
Abstract: Current pneumococcal vaccines are based on the protection offered by capsular polysaccharides from only a few from > 100 serotypes; therefore, serotype-independent vaccines composed of pneumococcal surface proteins are being developed. Despite the immense number of publications… read more here.
Keywords: process; pneumococcal surface; pneumococcal vaccines; development ... See more keywords
Removing surface proteins promote the retrogradation of wheat starch
Sign Up to like & getrecommendations! Published in 2020 at "Food Hydrocolloids"
DOI: 10.1016/j.foodhyd.2020.106437
Abstract: Abstract The effect of starch surface proteins on retrogradation of wheat starches were evaluated by rheometer, RVA, XRD, DSC, and TPA. An increase of the storage modulus and setback viscosity of starch pastes was observed… read more here.
Keywords: surface proteins; retrogradation wheat; starch;
Magnetic capture of polydopamine-encapsulated Hela cells for the analysis of cell surface proteins.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2017.10.009
Abstract: A novel method to characterize cell surface proteins and complexes has been developed. Polydopamine (PDA)-encapsulated Hela cells were prepared for plasma membrane proteome research. Since the PDA protection, the encapsulated cells could be maintained for… read more here.
Keywords: surface proteins; cell surface; cell; hela cells ... See more keywords
Nisin influence on the expression of Listeria monocytogenes surface proteins.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2020.103906
Abstract: In this work, a comparative analysis of the peripheral cell component (PCC) proteins of Listeria monocytogenes was carried out. The study was conducted on two set of samples consisting of bacteria treated with sub-lethal concentration… read more here.
Keywords: surface proteins; regulated proteins; listeria monocytogenes; nisin influence ... See more keywords
Evaluation of the protective efficacy of four newly identified surface proteins of Erysipelothrix rhusiopathiae.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.10.071
Abstract: Erysipelothrix rhusiopathiae is the causative agent of animal erysipelas and human erysipeloid. Bacterial surface proteins are promising vaccine candidates. We recently identified 3 E. rhusiopathiae surface proteins (GAPDH, HP0728, and HP1472) and characterized their roles… read more here.
Keywords: surface proteins; surface; gapdh; identified surface ... See more keywords
Multivalency Interface and g-C3N4 Coated Liquid Metal Nanoprobe Signal Amplification for Sensitive Electrogenerated Chemiluminescence Detection of Exosomes and Their Surface Proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b03427
Abstract: Exosomes derived vesicles and their surface anchored proteins by cells are extremely vital in intercellular communication, immuno-stimulation, and so on, which are promising in potential tumor biomarkers for disease diagnosis. However, the highly sensitive detection… read more here.
Keywords: surface proteins; detection exosomes; liquid metal; detection ... See more keywords
Profiling the Cellular Surfaceome by Furan-Based Protein Biotinylation
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.5c00597
Abstract: The cellular surfaceome is crucial for cellular homeostasis and communication, with surface proteins acting as receptors, transporters, and enzymes. However, comprehensive analysis of the surfaceome is challenging due to the hydrophobic nature and low abundance… read more here.
Keywords: profiling cellular; cellular surfaceome; surfaceome; biotinylation ... See more keywords
Efficient Strategy to Discover DNA Aptamers Against Low Abundance Cell Surface Proteins in Scarce Samples.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c03129
Abstract: Molecular recognition probes targeting cell surface proteins such as aptamers play crucial roles in precise diagnostics and therapy. However, the selection of aptamers against low-abundance proteins in situ on the cell surface, especially in scarce… read more here.
Keywords: abundance; cell surface; cell; selection ... See more keywords