General principles of binding between cell surface receptors and multi-specific ligands: A computational study
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1005805
Abstract: The interactions between membrane receptors and extracellular ligands control cell-cell and cell-substrate adhesion, and environmental responsiveness by representing the initial steps of cell signaling pathways. These interactions can be spatial-temporally regulated when different extracellular ligands… read more here.
Keywords: surface receptors; general principles; cell; multi specific ... See more keywords
Dysregulation in the Expression of Platelet Surface Receptors in Acute Coronary Syndrome Patients—Emphasis on P2Y12
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11050644
Abstract: Simple Summary Acute Coronary Syndrome is a disease of the circulatory system characterized by the partial or complete blockage of coronary arteries. In thrombosis, a major role is played by platelets—the smallest, anucleate, morphotic elements… read more here.
Keywords: coronary syndrome; surface receptors; acute coronary; expression ... See more keywords
Topological and Structural Plasticity of the Single Ig Fold and the Double Ig Fold Present in CD19
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11091290
Abstract: The Ig fold has had a remarkable success in vertebrate evolution, with a presence in over 2% of human genes. The Ig fold is not just the elementary structural domain of antibodies and TCRs, it… read more here.
Keywords: cell surface; surface receptors; cell; double fold ... See more keywords
Functional autoantibodies directed against cell surface receptors in systemic sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Scleroderma and Related Disorders"
DOI: 10.5301/jsrd.5000241
Abstract: Systemic sclerosis (SSc) is a complex and heterogeneous systemic autoimmune disease characterized by the presence of high serum levels of antibodies targeting a variety of self-antigens. In addition to autoantibodies directed against nuclear antigens, patients… read more here.
Keywords: functional autoantibodies; surface receptors; cell surface; systemic sclerosis ... See more keywords