A novel surfactant protein C gene mutation associated with progressive respiratory failure in infancy
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23493
Abstract: Mutations of the Surfactant Protein C (SPC) gene (SFTPC) have been associated with childhood interstitial lung disease (chILD) with variable age of onset, severity of lung disease, and outcomes. We report a novel mutation in… read more here.
Keywords: protein; surfactant protein; mutation; progressive respiratory ... See more keywords
Surfactant protein D as a marker for pulmonary complications in pediatric patients with sickle cell disease: Relation to lung function tests
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24257
Abstract: Surfactant protein D (SP‐D) is considered a candidate biomarker for lung integrity and for disease progression. read more here.
Keywords: protein; surfactant protein; disease; marker pulmonary ... See more keywords
Surfactant protein D is a biomarker of influenza‐related pediatric lung injury
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.25776
Abstract: Biomarkers that can risk‐stratify children with influenza virus lower respiratory infection may identify patients for targeted intervention. Early elevation of alveolar‐related proteins in the bloodstream in these patients could indicate more severe lung damage portending… read more here.
Keywords: biomarker influenza; lung; influenza related; related pediatric ... See more keywords
Divide & Conquer: Surfactant Protein SP-C and Cholesterol Modulate Phase Segregation in Lung Surfactant.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.06.059
Abstract: Lung surfactant (LS) is an essential system supporting the respiratory function. Cholesterol can be deleterious for LS function, a condition that is reversed by the presence of the lipopeptide SP-C. In this work, the structure… read more here.
Keywords: surfactant protein; phase; cholesterol; lung surfactant ... See more keywords
Air particulate matter pollution and circulating surfactant protein: A systemic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.129564
Abstract: OBJECTIVE Air particulate matter (PM) pollution is associated with the alterations in circulating pulmonary damage proteins. But there are not consistent results among the epidemiological studies. The aim of this study is to investigate the… read more here.
Keywords: surfactant protein; matter; air particulate; analysis ... See more keywords
Co-expression of surfactant protein A and chicken lung lectin in chicken respiratory system.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.03.018
Abstract: Chicken surfactant protein A (cSP-A) and chicken lung lectin (cLL) are C-type lectins that play important roles in pulmonary host defense responses. Herein, we explored the localization of cSP-A and cLL in the chicken respiratory… read more here.
Keywords: surfactant protein; cll; csp; expression ... See more keywords
Synchrotron radiation circular dichroism spectroscopy reveals that gold and silver nanoparticles modify the secondary structure of a lung surfactant protein B analogue.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr06107d
Abstract: Inhaled nanoparticles (NPs) depositing in the alveolar region of the lung interact initially with a surfactant layer and in vitro studies have demonstrated that NPs can adversely affect the biophysical function of model pulmonary surfactants… read more here.
Keywords: structure; spectroscopy; surfactant protein; synchrotron radiation ... See more keywords
A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2105228119
Abstract: Significance The Rab5 GTPase functions in early endosome (EE) fusion in the endocytic pathway. Here, we propose that RAB5B also has a noncanonical vesicular fusion function in the regulated secretion pathway that produces mature surfactant… read more here.
Keywords: variant rab5b; rab5b; surfactant protein; lung ... See more keywords
Impacts of lipopolysaccharide on fetal lung developmental maturity and surfactant protein B and surfactant protein C protein expression in gestational diabetes mellitus rats
Sign Up to like & getrecommendations! Published in 2021 at "Bioengineered"
DOI: 10.1080/21655979.2021.2013099
Abstract: ABSTRACT The rise of bioinformatics based on computer medicine provides a new method to reveal the complex biological data. This experiment is to explore the impacts of lipopolysaccharide on fetal lung developmental maturity and expressions… read more here.
Keywords: lung; group; fetal lung; gdm ... See more keywords
Surfactant protein-D, a potential mediator of inflammation in axial spondyloarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology"
DOI: 10.1093/rheumatology/key187
Abstract: Objectives Surfactant protein-D (SP-D), an innate immune defence molecule of the collectin family, is expressed in lungs and additional extrapulmonary epithelia. SP-D has immune modulatory and anti-microbial effects depending on its oligomerization. The ratio of… read more here.
Keywords: surfactant protein; potential mediator; mediator inflammation; axial spondyloarthritis ... See more keywords
A7441 Genetic polymorphism of surfactant protein D rs721917 may associated with severe obstructive sleep apnea hypopnea syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548185.45833.b1
Abstract: Objectives: Surfactant protein D (SP-D) are clinically established as potential serum biomarkers for in Chinese male patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Serum SP-D levels are affected by genetic variants. This case-control study… read more here.
Keywords: surfactant protein; hypopnea syndrome; apnea hypopnea; obstructive sleep ... See more keywords