Exploring the impact of surfactant type and digestion: Highly digestible surfactants improve oral bioavailability of nilotinib.
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DOI: 10.1021/acs.molpharmaceut.0c00305
Abstract: The scientific rational for selection of surfactant type during oral formulation development requires an in-depth understanding of the interplay between surfactant characteristics and biopharmaceutical factors. Currently, however, there is a lack of comprehensive knowledge of… read more here.
Keywords: chain; highly digestible; digestible surfactants; bioavailability nilotinib ... See more keywords
A novel chiral surfactant-type metallomicellar catalyst for asymmetric Michael addition in water.
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DOI: 10.1039/d0cc04410e
Abstract: A series of Schiff-based ligands consisting of both tertiary amines and lipophilic groups were designed and synthesized. Using these ligands, a new chiral surfactant-type metallomicellar catalyst was developed in water, and this was identified by… read more here.
Keywords: surfactant type; water; type metallomicellar; asymmetric michael ... See more keywords