Different Histopathologic Diagnoses in Patients With Clinically Diagnosed Hypertrophic Cardiomyopathy After Surgical Myectomy.
Sign Up to like & getrecommendations! Published in 2019 at "Circulation"
DOI: 10.1161/circulationaha.119.040129
Abstract: Circulation. 2019;140:344–346. DOI: 10.1161/CIRCULATIONAHA.119.040129 344 A lthough certain histopathologic findings (myocyte hypertrophy, disarray, interstitial fibrosis, and coronary artery dysplasia) are characteristic of hypertrophic cardiomyopathy (HCM)1, clinical recognition of phenocopies that masquerade clinically as HCM, despite… read more here.
Keywords: histopathologic diagnoses; surgical myectomy; clinically diagnosed; hcm ... See more keywords
Is surgical myectomy challenged by emergence of novel drug therapy with mavacamten?
Sign Up to like & getrecommendations! Published in 2022 at "Asian Cardiovascular and Thoracic Annals"
DOI: 10.1177/02184923221074414
Abstract: For 60 years, surgical myectomy has been the definitive treatment for symptomatic obstructive hypertrophic cardiomyopathy (HCM). Myectomy provides the opportunity to reverse heart failure symptoms in the vast majority of patient with low risk when… read more here.
Keywords: drug therapy; myectomy; surgical myectomy; therapy mavacamten ... See more keywords
Plasma metabolomic profiling of hypertrophic cardiomyopathy patients before and after surgical myectomy suggests postoperative improvement in metabolic function
Sign Up to like & getrecommendations! Published in 2021 at "BMC Cardiovascular Disorders"
DOI: 10.1186/s12872-021-02437-0
Abstract: Background Hypertrophic cardiomyopathy (HCM) is a common inherited heart disorder complicated by left ventricle outflow tract (LVOT) obstruction, which can be treated with surgical myectomy. To date, no reliable biomarkers for LVOT obstruction exist. We… read more here.
Keywords: hypertrophic cardiomyopathy; metabolomic profiling; metabolic function; lvot obstruction ... See more keywords