A Surprising Recipe for Designing Biased Ligands.
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DOI: 10.1021/acs.jmedchem.8b00764
Abstract: The determination of the potential value of receptor trafficking at melanocortin receptors has been hampered by the absence of known biased ligands. Heterobivalent MC4R ligands linking agonist to antagonist small peptidic moieties were designed and… read more here.
Keywords: recipe designing; biased ligands; surprising recipe; chemistry ... See more keywords