Pharmacokinetics, surrogate efficacy and safety evaluations of a new human plasma-derived fibrinogen concentrate (FIB Grifols) in adult patients with congenital afibrinogenemia.
Sign Up to like & getrecommendations! Published in 2021 at "Thrombosis research"
DOI: 10.1016/j.thromres.2020.12.026
Abstract: BACKGROUND AND AIMS Congenital afibrinogenemia is a rare coagulation disorder resulting from a deficiency in fibrinogen. This study assessed the pharmacokinetics, surrogate efficacy and safety of FIB Grifols, a new human plasma-derived fibrinogen concentrate, to… read more here.
Keywords: plasma; congenital afibrinogenemia; surrogate efficacy; efficacy ... See more keywords
Tolerability and surrogate efficacy parameters of a polymerized depot mixture pollen extracts without dilutional effect.
Sign Up to like & getrecommendations! Published in 2019 at "Immunotherapy"
DOI: 10.2217/imt-2019-0051
Abstract: Aim: To evaluate tolerability of subcutaneous immunotherapy, in a polymerized mixture (Olea europaea/Phleum pratense) depot presentation. Patients & methods: A total of 47 poly-allergic patients received: an abbreviated schedule with three injections at weekly intervals or a… read more here.
Keywords: efficacy parameters; surrogate efficacy; tolerability; tolerability surrogate ... See more keywords