Global longitudinal strain evaluated by speckle‐tracking echocardiography as a surrogate marker for predicting replacement fibrosis detected by magnetic resonance‐late gadolinium enhancement in patients with nonischemic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.22983
Abstract: This study aimed to investigate whether left ventricular (LV) global longitudinal strain (GLS) evaluated by speckle‐tracking echocardiography (STE) can be used as a surrogate marker for the detection of replacement fibrosis by late gadolinium enhancement… read more here.
Keywords: surrogate marker; tracking echocardiography; longitudinal strain; speckle tracking ... See more keywords
Surrogate Marker Evaluation: A Tutorial Using R
Sign Up to like & getrecommendations! Published in 2025 at "Statistics in Medicine"
DOI: 10.1002/sim.70048
Abstract: The practice of using a surrogate marker to replace a primary outcome in clinical studies has become widespread. Typically, the primary outcome requires long‐term patient follow‐up, is expensive, or is invasive or burdensome for patients… read more here.
Keywords: using surrogate; marker; surrogate marker; marker evaluation ... See more keywords
#1894 Disappearance of proteinuria is not a surrogate marker of improvement in IgA nephropathy
Sign Up to like & getrecommendations! Published in 2024 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfae069.1236
Abstract: IgA nephropathy is one of the most common chronic glomerulonephritis and 30-45% falls into chronic kidney disease over a period of 20 to 25 years. Lots of treatment regimens are tried such as RAAS blocker,… read more here.
Keywords: improvement; pathology; iga nephropathy; surrogate marker ... See more keywords
Using a surrogate marker for early testing of a treatment effect.
Sign Up to like & getrecommendations! Published in 2019 at "Biometrics"
DOI: 10.1111/biom.13067
Abstract: The development of methods to identify, validate and use surrogate markers to test for a treatment effect has been an area of intense research interest given the potential for valid surrogate markers to reduce the… read more here.
Keywords: surrogate marker; marker; treatment effect;
Suggested guide to using lactate gap as a surrogate marker in the diagnosis of ethylene glycol overdose
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Clinical Biochemistry"
DOI: 10.1177/00045632241292514
Abstract: Background Ethylene glycol (EG) poisoning, if not diagnosed rapidly, can lead to poor patient outcomes. Gas chromatography (GC) is primarily used for EG quantitation which is rarely available, and the turn-around time may be prolonged.… read more here.
Keywords: ethylene glycol; chemistry; lactate gap; surrogate marker ... See more keywords
Risk factors and utility of maximum carotid intima–media thickness as a surrogate marker for coronary artery stenosis
Sign Up to like & getrecommendations! Published in 2018 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s168926
Abstract: Background This study investigated the factors associated with coronary artery stenosis in outpatients. Furthermore, the usefulness of maximum carotid intima–media thickness (maximum-IMT) as a surrogate marker of coronary artery stenosis was evaluated. Methods We conducted… read more here.
Keywords: maximum imt; artery stenosis; surrogate marker; coronary artery ... See more keywords
The Prognostic Significance of p16 and its Role as a Surrogate Marker for Human Papilloma Virus in Oral Squamous Cell Carcinoma: An Analysis of 281 Cases
Sign Up to like & getrecommendations! Published in 2022 at "AntiCancer Research"
DOI: 10.21873/anticanres.15719
Abstract: Background/Aim: This study analyzed the expression of p16 in a large cohort of patients suffering from oral squamous cell carcinoma (OSCC) who received initial surgical therapy in order to evaluate the prognostic significance of p16… read more here.
Keywords: surrogate marker; p16 expression; p16; expression ... See more keywords
Recall interferon-γ responses against Coccidioides are a surrogate marker for vaccine response in dogs.
Sign Up to like & getrecommendations! Published in 2025 at "American journal of veterinary research"
DOI: 10.2460/ajvr.25.04.0119
Abstract: Objective To develop an interferon γ (IFN-γ) recall assay to detect a T-cell response following vaccination because antibody is seldom detected in Δcps1-vaccinated dogs. Methods Peripheral blood mononuclear cells were collected from naturally infected dogs… read more here.
Keywords: marker vaccine; response; vaccinated dogs; surrogate marker ... See more keywords
Validation of Controlled Attenuation Parameter Measured by FibroScan as a Novel Surrogate Marker for the Evaluation of Metabolic Derangement
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.739875
Abstract: Background/Objectives Renaming non-alcoholic fatty liver disease (NAFLD) to metabolic dysfunction-associated fatty liver disease (MAFLD) suggests a shift of emphasis to the accompanying metabolic disturbance. Controlled attenuation parameter (CAP) measured by FibroScan has been shown to… read more here.
Keywords: surrogate marker; cap; hepatic steatosis; cap 238 ... See more keywords
PIVKA-II as a surrogate marker for prognosis in patients with localized hepatocellular carcinoma receiving stereotactic body radiotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Radiation Oncology Journal"
DOI: 10.3857/roj.2021.00934
Abstract: Purpose This study aimed to determine the correlation between protein induced by vitamin K absence or antagonist-II (PIVKA-II) and stereotactic body radiotherapy (SBRT) in patients with hepatocellular carcinoma (HCC). Materials and Methods Sixty-one patients received… read more here.
Keywords: hepatocellular carcinoma; stereotactic body; surrogate marker; body radiotherapy ... See more keywords
Ratio of mean platelet volume to platelet count is a potential surrogate marker predicting liver cirrhosis
Sign Up to like & getrecommendations! Published in 2018 at "World Journal of Hepatology"
DOI: 10.4254/wjh.v10.i1.82
Abstract: AIM To provide a simple surrogate marker predictive of liver cirrhosis (LC). METHODS Specimens from 302 patients who underwent resection for hepatocellular carcinoma between January 2006 and December 2012 were retrospectively analyzed. Based on pathologic… read more here.
Keywords: surrogate marker; count; platelet; ratio ... See more keywords