US Food and Drug Administration Recommendations on the Use of Surrogate Measures as End Points in New Anti-infective Drug Approvals.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2019.5451
Abstract: Importance Regulatory and scientific guidelines stipulate that indirect, surrogate measures of patient benefit, such as a change in microbial culture status, should be used as primary end points only in pivotal trials of chronic conditions… read more here.
Keywords: primary end; end points; surrogate measures; anti infective ... See more keywords
Novel Surrogate Measures Based on a Similarity Network for Neural Architecture Search
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Access"
DOI: 10.1109/access.2023.3252887
Abstract: We propose two novel surrogate measures to predict the validation accuracy of the classification produced by a given neural architecture, thus eliminating the need to train it, in order to speed up neural architecture search… read more here.
Keywords: surrogate measures; similarity network; neural architecture; search ... See more keywords
Early surrogate measures for ablative therapies for intermediate-risk prostate cancer patients.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.6_suppl.241
Abstract: 241Background: Stereotactic body radiotherapy (SBRT) is increasingly used to treat patients with intermediate-risk prostate cancer (IR-PCa), but there is a lack of early surrogate measures in this ... read more here.
Keywords: surrogate measures; intermediate risk; risk prostate; prostate cancer ... See more keywords
The Cut-off Values of Surrogate Measures for Insulin Sensitivity in a Healthy Population in Korea according to the Korean National Health and Nutrition Examination Survey (KNHANES) 2007–2010
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Korean Medical Science"
DOI: 10.3346/jkms.2018.33.e197
Abstract: Background This study aimed to identify the gender-specific characteristics of the surrogate measures of insulin resistance and to establish valid cut-off values for metabolic abnormalities in a representative sample in Korea. Methods Data were collected… read more here.
Keywords: index; surrogate measures; measures insulin; cut ... See more keywords