Iron, Copper, and Zinc Concentration in Aβ Plaques in the APP/PS1 Mouse Model of Alzheimer's Disease Correlates with Metal Levels in the Surrounding Neuropil.
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DOI: 10.1021/acschemneuro.6b00362
Abstract: The metal ions of iron, copper, and zinc have long been associated with the aggregation of β-amyloid (Aβ) plaques in Alzheimer's disease; an interaction that has been suggested to promote increased oxidative stress and neuronal… read more here.
Keywords: iron copper; copper zinc; alzheimer disease; surrounding neuropil ... See more keywords