Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing
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DOI: 10.1093/nar/gkab003
Abstract: Abstract Dysfunction of splicing factors often result in abnormal cell differentiation and apoptosis, especially in neural tissues. Mutations in pre-mRNAs processing factor 31 (PRPF31) cause autosomal dominant retinitis pigmentosa, a progressive retinal degeneration disease. The… read more here.
Keywords: progenitor cells; retinal progenitor; differentiation; survival differentiation ... See more keywords